Lower costs lead to higher profits for AstraZeneca (AZN). A low cost leader can undercut rivals on price… … "Cost Advantages (AstraZeneca (AZN))" has a significant impact, so an analyst should put more weight into it. This qualitative factor will lead to a decrease in costs. "Cost Advantages (AstraZeneca (AZN))" is a difficult qualitative factor to defend, so competing institutions will have an easy time overcoming it.